Transplant Library Database Guide
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The Transplant Library is the bibliographic database of the Centre for Evidence in Transplantation (CET) which is based at the Nuffield Department of Surgical Sciences, University of Oxford, UK.

The Transplant Library contains records of:

  • randomised controlled trials (RCTs) in solid organ transplantation, from 1970 to present, including conference proceedings. Records of ongoing randomised controlled trials come from a number of trial registries.
  • Systematic reviews and meta-analyses of good quality from 2008 onwards.
  • Clinical practice guidelines from 2005
  • Studies of COVID-19 in solid organ transplantation

The CET uses a customized literature search in Medline (Ovid) and Cochrane Central bibliographic databases (with permission) to retrieve relevant transplantation records. The listing of RCTs is updated every two weeks. After the records are downloaded from these commercially-available databases, additional information is manually added to each record, based on certain indexing criteria, by CET personnel. Quality rating of methodology is available for most RCTs published since 2004 using both the Jadad scale (0-5) and the items concealed allocation and statistical analysis.

The Transplant Library includes a selection of systematic reviews (SR) and meta-analyses published from 2008 to the present. Systematic reviews and meta-analyses must meet a number of criteria before inclusion in the Transplant Library. The listing of reviews is updated every month. To be included in the Transplant Library a review should at least satisfy three of the following criteria:

  • The review addresses a clearly focused question and the describes the inclusion and exclusion criteria of the review (mandatory requirement)
  • The literature search is sufficiently rigorous to identify all relevant studies (mandatory requirement)
  • The study quality of included studies is assessed and reported
  • Sufficient details of the individual included studies are presented
  • An adequate description of the methodology used to analyse the data is included and the methods used are appropriate to the question

For more information or to receive training on the Transplant Library, please send your queries to [email protected]

Segments and Years of Coverage
Name   Years of Coverage
TRLI   1970 - present

The limit of databases that you can select for a multifile search session is based upon database segments rather than actual databases. The Ovid multifile segment limit is set at 120 to avoid impacting your search sessions. This database includes 1 segment.

This database is updated online bi-weekly.

Filters

If you experience difficulty in downloading references into EndNote this may be due to the correct import filter not being installed. Import filters can be downloaded from the EndNote (www.endnote.com) website within the Support and Services section.

The details of the required filter are:

  • Database - Transplant Library
  • Information Provider - Ovid SP

The import filter will need to be downloaded and saved into the filters folder of your EndNote package. This can be found by opening Program files, double clicking on EndNote and then opening the Filters folder. This may need to be performed by an administrator.

 

Fields
The following list is sorted alphabetically by field alias. Click a field name to see the description and search information.
All Fields in this Database
  Abstract (AB) ISSN (IS) Publication Type (PT)
  Additional Author Information (AO) Issue/Part (IP) Source (SO)
  Allocation Concealment (AC) JADAD Score Comment (JS) Start Date (SD)
  All Searchable Fields (AF) Journal Name (JN) Statistical Analysis (IT)
  Authors (AU) Journal Word (JX) Study Status (SS)
  Author Email (MA) Language (LG) Subject Headings (SH)
  Congress Abstracts (CO) Local Messages (LM) Subject Headings Word (HW)
  Country of Publication (CP) Non-MeSH Subject Headings (SX) Systematic Review Registration (SR)
  DOI (DO) Organ Type (OG) Title (TI)
  Electronic ISSN (ES) Original Title (OT) Trial Registration(TR)
  Estimated Completion (EC) Pagination (PG) Unique Identifier (UI)
  Exploded Subheading (XS) Patient Representation (PR) Update Code (UP)
  Floating Sub-heading (FS) Pediatric Patient (PP) URL (UR)
  Funding Information (FI) PMID (PM) Volume (VO)
  Funding Source (FN) Principal Investigator (PL) Year (YR)
  Institution (IN)    
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Default Fields for Unqualified Searches (MP): Searching for a term without specifying a field in Advanced search, or specifying .mp., defaults to the following ‘multi-purpose’ (.mp.) fields for this database: ab,sh,hw,ti.
  Abstract (AB) Subject Headings Word (HW) Title (TI)
  Subject Headings (SH)    
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Default Fields for Display, Print, Email, and Save: The following fields are included by default for each record.

  Abstract (AB) Jadad Score (0-5) (JD) Statistical Analysis (IT)
  Allocation Concealment (AC) Language (LG) Subject Headings (SH)
  Additional Author Information (AO) Local Messages (LM) Systematic Review Registration (SR)
  Authors (AU) Non-MeSH Subject Headings (SX) Title (TI)
  Congress Abstracts (CO) Original Title (OT) Trial Registration(TR)
  DOI (DO) Pediatric Patient (PP) Unique Identifier (UI)
  Funding Information (FI) PMID (PM) Update Code (UP)
  Institution (IN) Publication Type (PT) URL (UR)
  ISSN (IS) Source (SO)  
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All Fields for Display, Print, Email, and Save: Use the Select Fields button in the Results Manager at the bottom of the Main Search Page to choose the fields for a record.

  Abstract (AB) Funding Source (FN) Source (SO)
  Allocation Concealment (AC) Institution (IN) Start Date (SD)
  Additional Author Information (AO) Jadad Score (0-5) (JD) Statistical Analysis (IT)
  Authors (AU) Language (LG) Study Status (SS)
  Author Email (MA) Local Messages (LM) Subject Headings (SH)
  Congress Abstracts (CO) Non-MeSH Subject Headings (SX) Systematic Review Registration (SR)
  Country of Publication (CP) Original Title (OT) Title (TI)
  DOI (DO) Patient Representation (PR) Trial Registration(TR)
  Electronic ISSN (ES) Pediatric Patient (PP) Unique Identifier (UI)
  Estimated Completion (EC) PMID (PM) Update Code (UP)
  Funding Information (FI) Principal Investigator (PL) URL (UR)
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Elements of Source (SO) Field: Ovid searches the following fields as part of the record source.
  Issue/Part (IP) Pagination (PG) Volume (VO)
  Journal Name (JN)    
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The following list is sorted alphabetically by the two-letter label, and includes the relevant alias, at least one example for all searchable fields, and a description of the field.
Label Name / Example
AB Abstract [Word Indexed]
satisfaction.ab.

The Abstract (AB) field contains the abstract written by the author, as it appears in the printed article.

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AC Allocation Concealment [Phrase Indexed]
no.ac.

The Allocation Concealment (AC) field indicates to the user whether or not an adequate method of allocation concealment is described in the study (the field will indicate YES or NO). Concealment is considered adequate if patients and investigators who enrolled patients could not foresee assignment. Information in the Allocation Concealment field is added to the record by CET personnel.

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AF All Searchable Fields [Search Alias]
proteins.af.

All Fields (AF) is an alias for all of the fields which occur in the source documents, including value-added fields such as Subject Headings (SH).

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AO Additional Author Information [Word Indexed]
allocation.ao.

The Additional Author Information (AO) field contains additional information from the author about the methodology of the trial. Information in the Additional Author Information field is added to the record by CET personnel.

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AU Authors [Phrase Indexed]
abeywickrama k.au.

The Authors (AU) field contains the author(s) of the article. The format for authors is last name followed by the first name and/or one or more initials (for example, Smith JC or Smith J).

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CO Congress Abstracts [Phrase Indexed]
yes.co.

The Congress Abstracts (CO) field displays 'Yes' to indicate that the record is an abstract from a congress. Otherwise it does not display. Information in the Congress Abstracts field is added to the record by CET personnel.

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CP Country of Publication [Word Indexed]
united kingdom.cp.

The Country of Publication (CP) field contains the country in which a certain clinical practice guideline was published.

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DO DOI [Phrase Indexed]
101002 14651858cd005632pub3.do

The Digital Object Identifier (DO) field contains the registered DOI for electronic documents.

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EC Estimated Completion [Word Indexed]
2004.ec

The Estimated Completion (EC) field refers to the estimated completion date of the trial.

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ES Electronic ISSN [Phrase Indexed]
2146 8427.es.

The Electronic ISSN (ES) field contains the electronic International Standard Serial Number (eISSN) for the journal in which the article was published.

Like the ISSN, it appears as an 8-digit number, separated by a hyphen: 1089-4098.

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FI Funding Information [Phrase Indexed]
"industry funding and non industry funding".fi.

The Funding Information (FI) field describes the funding source for the study, which is usually included in the trial report or related trial reports. Funding is categorized as one of six categories: ‘Industry funding’, ‘non-industry funding’, ‘industry and non-industry funding’, ‘no funding was received for this study’, ‘funding not described’ or ‘funding not reported’.

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FN Funding Source [Word Indexed]
writing.fn.

The Funding Source (FN) field contains the details of the any external organisation, commercial company or charity that have funded the development of the guidelines.

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FS Floating Sub-heading [Phrase Indexed]
aa.fs.

Subheadings are qualifiers added to MeSH subject headings to refine their meaning. Terms such as "etiology" or "therapy", when combined with a MeSH heading, give a precise idea of what an article covers.

The Floating Subheadings (FS) field contains both the 2-letter codes, such as di and the full headings, such as direct or disease. These are displayed following the corresponding MeSH Subject Headings.

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HW Subject Headings Word [Word Indexed]
neoplasm.hw.

The Subject Headings Word (HW) field contains individual words from every subject heading in the Transplant Library. This field is used to retrieve every occurrence of a subject heading which includes a particular word, such as cancer. Results will display in either Subject Headings (SH) or Non-MeSH Subject Headings (SX).

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IN Institution [Word Indexed]
0116.in.

The Institution (IN) field contains affiliation information corresponding to the author field. This information is not standardized and can contain abbreviations, numbers, and postal and e-mail addresses. Enter the single most descriptive word in an institution (for example, harvard rather than university).

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IP Issue/Part [Word Indexed]
"1".ip.

The Issue/Part field (IP) contains the Issue and/or Part for a particular volume of a journal. Supplement information will also appear here when applicable. This field displays as part of the Source (SO) field.

The Issue/Part field is Word-indexed.

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IS ISSN [Phrase Indexed]
0009 9236.is.

The ISSN (IS) field contains the International Standard Serial Number (ISSN) for the journal in which an article was published. It appears as an 8-digit number, separated by a hyphen: 0028-4793.

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IT Statistical Analysis [Phrase Indexed]
Intention to Treat.it.

The Statistical Analysis (IT) field indicates to the user which of four different analysis strategies was used to analyse data.

Strict intention to treat: All patients are included in the analysis. Missing data are imputed in case of dropouts.

Available case analysis: Data are analysed according to the assigned intervention for every participant for whom the outcome was obtained. Missing data are not imputed.

Modified ITT: Data are analysed according to the assigned intervention. The analysis excludes participants who did not adhere to the protocol. For example, patients not transplanted or patients not receiving the study drug.

Per protocol analysis: Only patients who sufficiently complied with the protocol are included in the analysis.

Information in the Statistical Analysis field is added to the record by CET personnel.

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JD Jadad Score (0-5) [Phrase Indexed]
"2".jd.

The Jadad Score (0-5) (JD) field contains a numerical value (between 0-5) that indicates the study design/reporting quality of the clinical trial (0 being weakest and 5 being strongest). Information in the Jadad Score (0-5) field is added to the record by CET personnel.

When searching the Jadad Score (0-5) field, you must enclose number in quotation marks, as seen in the example above.

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JN Journal Name [Phrase Indexed]
american journal of transplantation.jn.
The Journal Name (JN) field contains the full name of the journal in which an article was published. The Journal Name field displays as part of the Source (SO) field.

Journal names are indexed as phrases; enter enough letters of the journal name to locate the name in the index (for example, "new engl" for "New England Journal of Medicine").

Common words (such as "the" and "of") ARE included in the JN index, but when "the" is the first word of a journal, it is deleted.

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JS JADAD Score Comment [Word Indexed]
publication.js.
The JADAD Score Comment (JS) contains the information whether the score was based on a previous study which was described as random; the randomisation scheme was described and appropriate; the study was described as double-blind and was appropriate; and there is a description of dropouts and withdrawals.

The JADAD Score Comment (JS) field displays in the Jadad Score (0-5) (JD) field.

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JX Journal Word [Word Indexed]
organs.jx.

The Journal Word (JX) field contains individual words from every journal name in the Transplant Library Database. This field is used to retrieve every occurrence of a journal which includes a particular word, such as "cancer."

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LG Language [Phrase Indexed]
english.lg.

The Language (LG) field contains the language of publication of an article.

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LM Local Messages [Display Only]

 

The Local Messages (LM) field contains messages created by the System Administrator to indicate information about journals held in your local library system.

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MA

Author Email [Word Indexed]
carpenter.ma.

The Author Email (MA) contains Email information about the Author.

The Author Email field is Word-indexed.

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OG

Organ Type [Word Indexed]
simultaneous.og.

The Organ Type (OG) field contains the name of the transplanted organ discussed in the article. Information in the Organ Type field is added to the record by CET personnel.

The Organ Type field is word-indexed.

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OT

Original Title [Word Indexed]
confronto.ot.

The Original Title (OT) includes any non-English titles in the original language. If the original title was in a non-Roman alphabet, then the OT is transliterated.

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PG Pagination [Word Indexed]
1007.pg.

The first page on which an article appears is indexed in the Pagination (PG) field. Often a journal title combined with the beginning page number is enough to locate a citation. The Pagination field displays as part of the Source (SO) field.

The Pagination field is Word-indexed.

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PL Principal Investigator [Phrase Indexed]
annetine gelijns mount sinai school of medicine usa.pl.

The Principal Investigator (PL) field contains the person or institution involved in the clinical trials research.

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PM PMID [Phrase Indexed]
"10030287".pm

The PMID (PM) field contains the unique identifier assigned to a record when it is created by PubMed.

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PP Pediatric Patient [Phrase Indexed]
yes.pp.

The Pediatric Patient (PP) field indicates to the user that the record included pediatric patients in its study (the field will indicate "Yes", otherwise, it will not display). Information in the Pediatric Patient field is added to the record by CET personnel.

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PR Patient Representation [Word Indexed]
completed.pr.

The Patient Representation (PR) field indicates whether a patient was represented on clinical guideline working group.

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PT Publication Type [Phrase Indexed]
randomised controlled trial.pt.

The Publication Type (PT) field contains one or more terms used to describe the type of the source document, such as Randomized Controlled Trial or Systematic Review. Publication types included in the Transplant Library are randomized controlled trials, systematic reviews, clinical practice guidelines, studies based on registry data and records of ongoing RCTs (trial registry record).

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QS Quality Score [Phrase Indexed]
available.qs.
 

The Quality Score (QS) field displays whenever a record contains the following: Allocation Concealment (AC), Statistical Analysis (IT), or Jadad Score (0-5) (JD).

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SD Start Date [Word Indexed]
2004.sd.
The Start Date (SD) field states the date when the clinical trial study was first conducted.
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SH Subject Headings [Phrase Indexed]
0 abatacept.sh.
The Subject Headings (SH) field contains terms used by indexers to describe the subject content of an article. Results will display in either Subject Headings (SH) or Non-MeSH Subject Headings (SX).
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SO Source [Display Only]

The Source (SO) field includes a display of all the basic information needed to locate a citation, including the full Journal Name (JN), Volume (VO), Issue/Part (IP), and Pagination (PG).

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SR Systematic Review Registration [Word Indexed]
crd42012001720.sr.
The Systematic Review Registration (SR) field refers to the registration of a systematic review or systematic review protocol in a register for systematic reviews, for example the PROSPERO register. The unique registration number refers to a record that includes key information about the design and conduct of a systematic review.
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SS Study Status [Word Indexed]
completed.ss.
The Study Status (SS) field defines the state of the study being conducted.
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SX Non-MeSH Subject Headings [Display Only]
The Non-MeSH Subject Headings (SX) field contains terms used by indexers to describe the subject content of an article.
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TI Title [Word Indexed]
gastrointestinal.ti.

The Title (TI) field contains the title of a document in English.

The Title field is Word-indexed. Common words (such as "of" or "the") will display in documents but do not appear in the Title index. However, the word "a", which is a stopword in other fields, can be searched in titles.

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TR Trial Registration [Word Indexed]
NCT00251004.tr.

The Trial Registration (TR) field includes the unique trial registration number that has been assigned by a trial registry, such as clinicaltrials.gov.

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UI Unique Identifier [Phrase Indexed]
1016.ui.
The Unique Identifier (UI) field contains a numeric code that uniquely identifies a record within the Transplant Library.
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UP Update Code [Phrase Indexed]
20160713.up.
The Update Code (UP) field contains the date (YYYYMMDD format) that the record was last updated in the Transplant Library.
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UR URL [Word Indexed]
722892135.ur.
The URL (UR) field contains the electronic URL addresses present in the database. The format is variable, but follows the Internet-common practice for URLs.
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VO Volume [Word Indexed]
"14".vo.

The Volume (VO) field consists of the volume of a serial publication. The Volume field displays as part of the Source (SO) field.

The Volume field is Word-indexed.

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XS Exploded Sub-headings [Phrase Indexed]
tu.xs.

The Exploded Subheadings (XS) field contains the two-letter codes for the pre-exploded subheadings. Sometimes multiple MeSH Subheadings can be logically grouped together. Such related groups of subheadings are "pre-exploded" under one broad subheading. This means that all the grouped subheadings can be retrieved together by searching on the "pre-exploded" version of the broad subheading.

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YR Year [Phrase Indexed]
2017.yr.

The Year (YR) field contains the year (as a 4-digit number) in which an article was published.

The Year field is Phrase-indexed.

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Advanced Searching
You can use special search syntax listed below to combine search terms or strategically develop a search. Full documentation is provided in the Advanced Searching Techniques section of the Online Help.
Operator Syntax Search Example Sample Results
OR x or y gallbladder or gallstones "Gallbladder carcinomas were detected in 16 patients"

The OR operator retrieves records that contain any or all of the search terms. For example, the search heart attack or myocardial infarction retrieves results that contain the terms heart attack, myocardial infarction or both terms; results are all inclusive. You can use the OR operator in both unqualified searches and searches applied to a specific field.
AND x and y liver and disease "Transplantation was indicated due to end-stage liver disease"

The AND operator retrieves only those records that include all of the search terms. For example, the search blood pressure and stroke retrieves results that contain the term blood pressure and the term stroke together in the same record; results are exclusive of records that do not contain both of these terms. You can use the AND operator in both unqualified searches and searches applied to a specific field.
NOT x not y lung not cancer "Inhaled nitric oxide for modulation of ischemia-reperfusion injury in lung transplantation"

The NOT operator retrieves records that contain the first search term and excludes the second search term. For example, the search health reform not health maintenance organizations retrieves only those records that contain the term health reform but excludes the term health maintenance organizations. In this way, you can use the NOT operator to restrict results to a specific topic.
You can use the NOT operator in both unqualified searches and searches applied to a specific field.
Adjacency (ADJ) x y blood adj pressure "Blood Pressure Regulation"

The Adjacent operator (ADJ) retrieves records with search terms next to each other in that specific order. You do not need to separate search terms manually by inserting ADJ between them, because when you separate terms with a space on the command line, Ovid automatically searches for the terms adjacent to one another. For example, the search blood pressure is identical to the search blood adj pressure.
Defined Adjacency (ADJn) x ADJn y Immunosuppression adj3 Mycophenolate "prospective, randomized trial of steroid withdrawal in low risk renal transplant recipients on triple immunosuppression consisting of mycophenolate mofetil (MMF), microemulsion cyclosporine (CSA), and prednisone"

The defined adjacency operator (ADJn) retrieves records that contain search terms within a specified number (n-1) of words from each other in any order (stop-words included). To use the adjacency operator, separate your search terms with ADJ and a number from 1 to 99 as explained below:

           ADJ1     Next to each other, in any order
           ADJ2     Next to each other, in any order, up to 1 word in between
           ADJ3     Next to each other, in any order, up to 2 words in between
           ADJ99   Next to each other, in any order, up to 98 words in between

For example, the search physician adj5 relationship retrieves records that contain the words physician and relationship with a maximum of four words in between in either direction. This particular search retrieves records containing such phrases as physician patient relationship, patient physician relationship, or relationship between cancer patient and physician.
Please note Ovid’s order of operation handles terms within parentheses first. Therefore it is recommended to apply the ADJn operator in one-on-one operations to avoid missing out on results. E.g. stroke adj4 (blood pressure or high blood pressure) could potentially miss out on some combinations of stroke with high blood pressure. The optimum way to execute this on Ovid is: (stroke adj4 blood pressure) OR (stroke adj4 high blood pressure).
Frequency (FREQ) x.ab./FREQ=n blood.ab/FREQ=3 "A randomized controlled trial was conducted to clarify the effectiveness of intraoperative blood salvage in reducing blood loss. "

The frequency operator (FREQ) lets you specify a threshold of occurrence of a term in the records retrieved from your search. Records containing your search term are retrieved only if the term occurs at least the specified (n) number of times. In general, records that contain many instances of your search term are more relevant than records that contain fewer instances. The frequency operator is particularly useful when searching a text field, such as Abstract or Full Text, for a common word or phrase.
Unlimited Truncation ($) x$ suff$ "dogs suffering with"
"grain protein content and size sufficiently"

Unlimited truncation retrieves all possible suffix variations of the root word indicated. To apply unlimited truncation to a term, type the root word or phrase followed by either of the truncation characters: $ (dollar sign) or * (asterisk). For example, in the truncated search disease*, Ovid retrieves the word disease as well as the words diseases, diseased, and more.
Limited Truncation ($) x$n dog$1 "Our study suggests that conclusions made in dogs about the influence of splenectomy on acute tubular necrosis may be applied to humans"

Limited truncation specifies a maximum number of characters that may follow the root word or phrase. For example, the truncated search dog$1 retrieves results with the words dog and dogs; but it does not retrieve results with the word dogma.
Mandated Wildcard (#) xx#y wom#n "Alzheimer's disease in women"
"There were 14 men and 1 woman of mean age"

Searching with a mandated wildcard retrieves all possible variations of a word in which the wildcard is present in the specified place. You can use it at the end of a term to limit results to only those that contain the word plus the mandated character. For example, the search dog# retrieves results that contain the word dogs, but not those that contain the word dog, effectively limiting results to only those that contain the plural form of the word. The mandated wild card character (#) is also useful for retrieving specialized plural forms of a word. For example, the search wom#n retrieves results that contain both woman and women. You can use multiple wild cards in a single query word.
Optional Wildcard (?) xx?y colo?r "A prospective study of colour Doppler ultrasound and isotope imaging in the detection of early renal transplant rejection"

The optional wild card character (?) can be used within or at the end of a search term to substitute for one or no characters. This wild card is useful for retrieving documents with British and American word variants since it specifies that you want retrieval whether or not the extra character is present. For example, the optional wild card search colo?r retrieves results that contain the words color or colour. You can use multiple wild cards in a single query word.
Literal String ("") "x / y" "heart/lung"

"Data from 48 lung or heart/lung transplant recipients"

"n" "3".vo

Cochrane Database of Systematic Reviews. 3 CD005442, 2010.”

Quotation marks can be used to retrieve records that contain literal strings, when the string includes special characters, such as a forward slash (/).

Quotation marks can also be used to retrieve records that contain numbers that may otherwise be confused for earlier searches. In the example, a search for 3.vo would limit the string from your third search in your search history to the Volume (VO) field. By including the number in quotation marks, the search will retrieve documents with a 3 in the volume number.

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Stopwords

The Ovid search engine applies so called "run-time stopword processing". This means the search engine on the fly ignores the stopwords: and, as, by, for, from, in, is, of, on, that, the, this, to, was, were & with.

Therefore a search: at risk for diabetes.ti will also find: at risk of diabetes. The distance of one word in between is kept, but the stopword "for" is ignored.

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Limits
The following limits are available for this database. See Database Limits in the Ovid Online Help for details on applying limits.

Limit

Syntax
Abstracts Sentence Syntax:
limit 1 to abstracts
Command Syntax ..l/ ab=y
A limit to Abstracts restricts retrieval to documents which include an abstract.
Clinical Practice Guideline Sentence Syntax:
limit 1 to clinical practice guideline
A limit to Clinical Practice Guideline will restrict retrieval to records that are labeled as clinical practice guideline.
English Language Sentence Syntax:
limit 1 to english language
A limit to English Language restricts retrieval to articles which are written in the English language.
Exclude Congress Abstracts Sentence Syntax:
limit 1 to exclude congress abstracts
A limit to Exclude Congress Abstracts restricts retrieval to articles which are not congress proceedings.
Full Text Sentence Syntax:
limit 1 to full text

A limit to Full Text restricts retrieval to records that have links to full text. Both Ovid full text and external full text are included in this limit.

Heart Transplant Sentence Syntax: limit 1 to heart transplant
A limit to Heart Transplant restricts retrieval to records pertaining to heart transplants.
Heart/Lung Transplant Sentence Syntax: limit 1 to heart/lung transplant
A limit to Heart/Lung Transplant restricts retrieval to records pertaining to heart/lung transplants.
Intestine Transplant Sentence Syntax: limit 1 to liver transplant
A limit to Intestine Transplant will restrict retrieval to records pertaining to intestine transplants.
Kidney Transplant Sentence Syntax: limit 1 to kidney transplant
A limit to Kidney Transplant restricts retrieval to records pertaining to kidney transplants.
Language Sentence Syntax: limit 1 to french
A limit to Language restricts retrieval to a particular language, such as Chinese, French, or German.
Latest Update Sentence Syntax: limit 1 to latest update
A limit to Latest Update restricts retrieval to records which were most recently added to the database.
Liver Transplant Sentence Syntax: limit 1 to liver transplant
A limit to Liver Transplant restricts retrieval to records pertaining to liver transplants.
Lung Transplant Sentence Syntax: limit 1 to lung transplant
A limit to Lung Transplant restricts retrieval to records pertaining to lung transplants.
Ovid Full Text Available Sentence Syntax: limit 1 to ovid full text available
 

A limit to Ovid Full Text Available restricts retrieval to those citations where an Ovid full text link is available. When viewing a citation with full text available use the LINK button to display the full text.

Pancreas Transplant Sentence Syntax: limit 1 to pancreas transplant
A limit to Pancreas Transplant restricts retrieval to records pertaining to pancreas transplants.
Pediatric Patient Sentence Syntax:
limit 1 to pediatric patient
A limit to Pediatric Patient restricts retrieval to articles which included pediatric patients in the study.
Publication Type Sentence Syntax:
limit 1 to randomised controlled trial
The limit to Publication Type can be applied to restrict retrieval to records according to one of the five publication types, ie Clinical Practice Guidelines, Randomised Controlled Trials, Systematic Reviews, Trial Registry records (ongoing trials) or studies based on registry data.
Publication Year Sentence Syntax:
limit 1 to yr="1990 - 2006"
Command Syntax: ..l/ yr=1997
A limit to Publication Year restricts retrieval to any of the years which this database covers.
Quality Score Sentence Syntax: limit 1 to quality score
  A limit to Quality Score restricts retrieval to records that contain the following: Allocation Concealment (AC), Statistical Analysis (IT), or Jadad Score (0-5) (JD).
Randomised Controlled Trial Sentence Syntax: limit 1 to randomised controlled trial
A limit to Randomised Controlled Trial restricts retrieval to records that are labeled as randomised controlled trials (RCTs).
Registry Data Study Sentence Syntax: limit 1 to registry data study
A limit to Registry Data Study will restrict retrieval to records that are labeled as registry data study.
Simultaneous Pancreas
/Kidney Transplant
Sentence Syntax: limit 1 to spk transplant
limit 1 to simultaneous pancreas/kidney transplant
A limit to Simultaneous Pancreas/Kidney Transplant (SPK) restricts retrieval to records pertaining to SPK transplants.
Systematic Review Sentence Syntax: limit 1 to "systematic review"
A limit to Systematic Review restricts retrieval to records that are labeled as systematic reviews.
Trial Registry Record Sentence Syntax: limit 1 to trial registry record
A limit to Trial Registry Record will restrict retrieval to records that are labeled as trial registry record.
Various Organ Transplant Sentence Syntax: limit 1 to various organ transplant

A limit to Various Organ Transplant restricts retrieval to records where:

  • the organ transplanted is not specified, or
  • studies include multiple types of organ transplants.
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Tools

The following Search Tools are available for this database. For specific information on using these tools, refer to the Ovid Online Help linked below.

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Changing to this Database
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Sample Documents
Sample 1
Unique Identifier
   9736
Authors
   Drechsler C, Pihlstrom H, Meinitzer A, Pilz S, Tomaschitz A, Abedini S, Fellstrom B, Jardine AG, 
   Wanner C, Marz W, Holdaas H.
Author Email
   [email protected]
Title
   Homoarginine and Clinical Outcomes in Renal Transplant Recipients: Results From the Assessment 
   of Lescol in Renal Transplantation Study.
Institution
   1 Division of Nephrology, Department of Medicine, University Hospital Wurzburg, Wurzburg, 
   Germany. 2 Comprehensive Heart Failure Centre, University Hospital of Wurzburg, Wurzburg, 
   Germany. 3 Department of Organ Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, 
   Norway. 4 Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of 
   Graz, Graz, Austria. 5 Department of Epidemiology and Biostatistics, EMGO Institute for Health 
   and Care, Research, VU University Medical Centre, Amsterdam, the Netherlands. 6 Division of 
   Endocrinology and Metabolism, Department of Internal Medicine, Medical, University of Graz, 
   Graz, Austria. 7 Department of Cardiology, Medical University of Graz, Graz, Austria. 8 Specialist 
   Clinic for Rehabilitation Bad Aussee, Bad Aussee, Austria. 9 Division of Nephrology, Department of 
   Medicine, Sykehuset i Vestfold, Tonsberg, Norway. 10 Division of Nephrology, Department of 
   Internal Medicine, Uppsala University Hospital, Uppsala, Sweden. 11 Institute of Cardiovascular 
   and Medical Sciences, University of Glasgow, Glasgow, UK. 12 Department of Medicine V 
   (Nephrology, Hypertensiology, Endocrinology, Rheumatologie) Mannheim Medical Faculty 
   Mannheim, University of Heidelberg, Mannheim, Germany. 13 Clinical Institute of Medical and 
   Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria. 14 Synlab Academy, 
   Synlab Services, Mannheim, Germany.
Source Transplantation. 99(7): 1470-6, 2015.
Publication Type Randomised Controlled Trial
Organ Type Kidney transplant Language English Funding Information Industry funding Allocation Concealment Yes Statistical Analysis Intention to treat Jadad Score (0-5) 5 (Score based on previous publication - Holdaas, H. et al. Nephrology Dialysis Transplantation 20(5): 974-980. 2005) Abstract BACKGROUND: Despite improvements in kidney transplantation, complications, including cardiovascular morbidity and graft loss, contribute to reduced graft and patient survival. The amino acid homoarginine exerts a variety of beneficial effects that may be relevant for cardiovascular and graft outcomes, which is investigated in the present study. METHODS: Homoarginine was measured in 829 renal transplant recipients participating in the placebo group of the Assessment of Lescol in Renal Transplantation study. Mean follow-up was 6.7 years. By Cox regression analyses, we determined hazard ratios (HRs) to reach prespecified, adjudicated endpoints according to baseline homoarginine levels: major adverse cardiovascular events (n = 103), cerebrovascular events (n = 53), graft failure or doubling of serum creatinine (n = 140), noncardiovascular mortality (n = 51), and all-cause mortality (n = 107). RESULTS: Patients mean age was 50 +/- 11 years, homoarginine concentration was 1.96 +/- 0.76 mumol/L, and 65% were men. Patients in the lowest homoarginine quartile (<1.40 mumol/L) had an adjusted 2.6-fold higher risk of cerebrovascular events compared to those in the highest quartile (>2.34 mumol/L) (HR, 2.56; 95% confidence interval [95% CI], 1.13-5.82). Similarly, the renal endpoint occurred at a significantly increased rate in the lowest homoarginine quartile (HR, 2.34; 95% CI, 1.36-4.02). For noncardiovascular and all-cause mortality, there was also increased risk associated with the lowest levels of homoarginine, with HRs of 4.34 (95% CI, 1.63-10.69) and 2.50 (95% CI, 1.38-4.55), respectively. CONCLUSIONS: Low homoarginine is strongly associated with cerebrovascular events, graft loss and progression of kidney failure and mortality in renal transplant recipients. Whether interventions with homoarginine supplementation improve clinical outcomes requires further evaluation.
Subject Headings Kidney Transplantation Adult Biomarkers / bl [Blood] Cardiovascular Diseases / bl [Blood] Cardiovascular Diseases / di [Diagnosis] *Cardiovascular Diseases / et [Etiology] Cardiovascular Diseases / mo [Mortality] Chi-Square Distribution Creatinine / bl [Blood] Disease Progression Europe *Fatty Acids, Monounsaturated / tu [Therapeutic Use] Female Graft Rejection / bl [Blood] Graft Rejection / di [Diagnosis] *Graft Rejection / et [Etiology] Graft Rejection / mo [Mortality] Graft Survival *Homoarginine / bl [Blood] Humans *Hydroxymethylglutaryl-CoA Reductase Inhibitors / tu [Therapeutic Use] *Indoles / tu [Therapeutic Use] *Kidney Transplantation / ae [Adverse Effects] Kidney Transplantation / mo [Mortality] Male Middle Aged Multivariate Analysis North America Proportional Hazards Models Prospective Studies Renal Insufficiency / bl [Blood] Renal Insufficiency / di [Diagnosis] *Renal Insufficiency / et [Etiology] Renal Insufficiency / mo [Mortality] Risk Factors Time Factors Treatment Outcome ISSN 0041-1337 ISSN Electronic 1534-6080 Update Code 20170627
Sample 2
Unique Identifier
   9964
Year
   2014   
Principal Investigator
   Wiwat Chancharoenthana, MD.,MSc. Chulalongkorn University, Thailand
Title
   Protocol-Specified Modification of Immunosuppression Directed to Protocol Biopsy in Kidney 
   Transplantation.
Trial Registration Clinicaltrials.gov - NCT02294097 Start Date November 2014 Estimated Completion December 2016 Study Status Recruiting
Publication Type Trial Registry Record
Organ Type Kidney transplant
Funding Information Non-industry funding Subject Headings Kidney Transplantation URL http://ClinicalTrials.gov/show/N... Update Code 20170627
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