IMS Patent Focus Database Guide
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IMS Patent Focus is the premier source of information on pharmaceutical product patent families, allowing the user to access the product patent family directly from the generic name of the drug, and to see the patent position by expiry date across countries. The database covers the product patent position for over 1200 marketed drugs or promising drugs in phase III or above clinical trials.

Segments and Years of Coverage
Name   Years of Coverage
PTI   1994- present

The limit of databases that you can select for a multifile search session is based upon database segments rather than actual databases. The Ovid multifile segment limit is set at 120 to avoid impacting your search sessions. This database includes 1 segment.

This database is updated online monthly.

 

 

Fields
The following list is sorted alphabetically by field alias. Click a field name to see the description and search information.
All Fields in this Database
  Accession Number (AN) Heading Words (HW) Patent Family (FN)
  CAS Registry Numbers (RN) Highest Phase (HP) Patent Filing Date (FD)
  Chemical Name (CN) Image (IM) Patent Number (PN)
  Country Comments (CT) Indication (IC) Patent Publication Date (PP)
  Descriptor (DE) Indication Word (IW) Patent Type (TP)
  Document Count (DZ) Latest Change (LC) Priority Details (PR)
  Drug Name (DN) Mechanism of Action (ME) Registry Number Words (RW)
  Drug Word (DW) Patent Application Information (AI) SPC Expiry Dates (SP)
  EphMRA code (CC) Patent Assignee (PA) Synonyms (SY)
  Expiry Information (EI) Patent Assignee Word (AW) Update Code (UP)
  General Comments (GC) Patent Country (CY)  
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Default Fields for Unqualified Searches: Searching for a term without specifying a field searches the following fields.
  Drug Word (DW) Indication Word (IW) Patent Assignee Word (AW)
  General Comments (GC) Mechanism of Action (ME)  
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Default Fields for Display, Print, Email, and Save: The following fields are included by default for each record.

  Accession Number (AN) Highest Phase (HP) Patent Filing Date (FD)
  CAS Registry Numbers (RN) Indication (IC) Patent Number (PN)
  Chemical Name (CN) Latest Change (LC) Patent Publication Date (PP)
  Drug Name (DN) Mechanism of Action (ME) Patent Type (TP)
  EphMRA code (CC) Patent Assignee (PA) Priority Details (PR)
  Expiry Information (EI) Patent Country (CY) SPC Expiry Dates (SP)
  General Comments (GC) Patent Family (FN) Synonyms (SY)
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All Fields for Display, Print, Email, and Save: Use the Select Fields button in the Results Manager at the bottom of the Main Search Page to choose the fields for a record.

  Accession Number (AN) Indication (IC) Patent Filing Date (FD)
  CAS Registry Numbers (RN) Latest Change (LC) Patent Number (PN)
  Chemical Name (CN) Mechanism of Action (ME) Patent Publication Date (PP)
  Drug Name (DN) Patent Application Information (AI) Patent Type (TP)
  EphMRA code (CC) Patent Assignee (PA) Priority Details (PR)
  Expiry Information (EI) Patent Country (CY) SPC Expiry Dates (SP)
  General Comments (GC) Patent Family (FN) Synonyms (SY)
  Highest Phase (HP)    
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The following list is sorted alphabetically by the two-letter label, and includes the relevant alias, at least one example for all searchable fields, and a description of the field.
Label Name / Example
AI

Patent Application Information [Word Indexed]
5184.ai.
19940810.ai.

  The Patent Application Information (AI) field contains the publication date of any published patent application in the Patent Country and the number of a published patent application in the Patent Country if it differs from the granted patent number. If a year is needed, the display format is YY/Application Number Application Date.

Searching may be done on the Patent Application number or the Application date.

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AN

Accession Number [Phrase Indexed]
0052871.an.

 

The Accession Number (AN) field is a unique number assigned to each document.
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AW

Patent Assignee Word [Word Indexed]
SmithKline Beecham.aw.

  The Patent Assignee Word (AW) index contains the name of the company, which holds or applied for the patent. The Patent Assignee field is useful for seeing which company originated a drug if a company merger occurred after patenting the drug.
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CC

EphMRA Code [Word Indexed]

  The EphMRA (CC) field contains the alphanumeric code assigned by the European Pharmaceutical Marketing Research Association to describe the therapeutic use of the product. The text to describe the code is also included in the field.
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CN

Chemical Name [Word Indexed]
tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid.cn.
bisphosphonic acid.cn.

  The Chemical Name (CN) field contains the systematic name for the compound.
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CT

Country Comments [Word Indexed]
oapi.ct
pharmaceutical.ct

  The Country Comments (CT) field contains notes and explanations of any factors affecting the patent in the country specified in the Patent Country field, for example, GATT patent term resets in the USA.
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CY

Patent Country [Phrase Indexed]
Bulgaria.cy.

  The Patent Country (CY) field contains the country in which the patent has been filed or granted. The Patent Country (CY) index is browsable.
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DE

Descriptors [Phrase Indexed]
biotechnology.de.
platelet antiaggregant.de.

  The Descriptors (DE) field contains the terms for Indications, Mechanism of Action, and Drug Name.
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DN

Drug Name [Phrase Indexed]
abacavir.dn

  The Drug Name (DN) field contains the complete name or code by which a product is currently known, depending on the stage of development and the type of product. In some cases the drug name is not available. When this is the case the Lab Code will be used or, if it is not available, the Trade Name. In these instances there will be duplication between the Drug Name field and the Synonym (SY) field.

When available the drug name is followed by the nomenclature, which is the naming system for the drug's generic name (ex. USAN or pINN).

The nomenclature is not found in every record and is for display only.

The index is browsable.

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DW

Drug Word [Word Indexed]
urapidil.dw

  The Drug Word (DW) index contains the name or code by which a product is currently known, depending on the stage of development and the type of product.
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EI

Expiry Information [Word Indexed]
20080319.ei.

  The Expiry Information (EI) field contains the estimated expiry date for the product as well as any additional comments indicating factors which may affect the patent expiry, for example, if the patent has been extended or if supplementary protection has been sought or granted.
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FD

Patent Filing Date [Phrase Indexed]
19860227.fd.

  The Patent Filing Date (FD) field is the date the application for a patent was submitted (filed) in the Patent Country - this is often the start date for the patent term. The date is in YYYYMMDD format.
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FN

Patent Family [Phrase Indexed]
eflornithine.fn.

  The preferred name for a product - usually the INN- with qualifiers if a drug has more than one patent family, for example, NIFEDIPINE (COMPOSITION, 1980).
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GC

General Comments [Word Indexed]
bacterium.gc
package.gc

  The General Comments (GC) field contains the notes and explanations of any factors relevant to all of the patents in a given patent family for a drug.
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HP

Highest Phase [Phrase Indexed]
marketed.hp.

  The Highest Phase (HP) field contains the highest phase of the drug's development.
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HW

Heading Words [Word Indexed]
adrenergic.hw

  The Heading Words (HW) index contains the words for Indications, Mechanism of Action, and Drug Name.
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IC

Indication [Phrase Indexed]
benign prostate hypertrophy.ic.
viral infection.ic

  The Indication (IC) field contains the medical indication for the product described. This index is browsable.
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IW

Indication Word [Word Indexed]
dysuria.iw
hepatitis.iw.

  The Indication Word (IW) index contains information on the specific diseases for which the drug is being used.
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LC

Latest Change [Phrase Indexed]
20030328.lc.

  The Latest Change field (LC) indicates the most recent change to the record.
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ME

Mechanism of Action [Word Indexed]
beta.me.
lipid.me.

  The Mechanism of Action (ME) field contains one or more mechanisms of action that apply to that compound in a disease. Multiple mechanisms of action can be added for a single drug.
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PA

Patent Assignee [Phrase Indexed]
lilly.pa.

  The Patent Assignee (PA) is the name of the company, which holds or applied for the patent. The Patent Assignee field is useful for seeing which company originated a drug if a company merger occurred after patenting the drug. The country name is included for display only.
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PN

Patent Number [Phrase Indexed]
503238.pn.

  The Patent Number (PN) field contains the number of the granted patent document in the Patent Country. If a year is needed, the format is YY/Patent Number. Japanese patents (examined applications) and applications are always given a western year; the Mikado year is not used.

Only the patent number is indexed. The two digit YY is for display only.

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PP

Patent Publication Date [Phrase Indexed]
19930526.pp.

  The Patent Publication Date (PP) field contains the date of publication of the granted patent document in the Patent Country. The date is in YYYYMMDD format.
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PR

Priority Details [Word Indexed]
japan.pr
107879.pr.

  The Priority Details (PR) contain the date of filing the priority documents in the country given followed by the country and assigned number for the original application for a patent.
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RN

CAS Registry Number [Phrase Indexed]
26787-78-0.rn.

  The CAS Registry Number (RN) field contains the CAS registry number for the compound’s ingredients as well as the ingredient name.

The Registry Number index contains the number only for searching. The Registry Number Words (RW) index should be used for searching words.

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RW

Registry Number Words [Word Indexed]
monohydrochloride.rw.

  The Registry Number Words (RW) index contains the ingredients associated with the registry number for the compound.

Results will display in the RN field.

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SP

SPC Expiry Date [Phrase Indexed]
20050629.sp.

  The SPC Expiry Date (SP) field is the dates when any Supplementary Protection Certificate for the product should expire. Complementary Protection Certificate (CCP) expiry, available in France and Italy, for a limited period is also given here.
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SY

Synonyms [Word Indexed]
benazepril.sy.
hydrochloride.sy.

  The Synonyms (SY) field contains names and codes other than those listed in the Drug Name (DN) field by which a compound is known. Brand names and lab codes are found in this index.
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TP

Patent Type [Phrase Indexed]
product.tp.

  The type of claim(s) to the drug in the Patent Country, for example, Product, Process.
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UP

Update Code [Word Indexed]
201307.up

  The Update Code field (UP) contains the Year, Month and Day (YYYYMMDD) the file was updated.
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Advanced Searching
You can use special search syntax listed below to combine search terms or strategically develop a search. Full documentation is provided in the Advanced Searching Techniques section of the Online Help.
Operator Syntax Search Example Sample Results
OR x or y

specific or generic

"In addition, there are specific or generic product claims to lamivudine salicylate and emtricitabine salicylate and their hydratesin many patents."

 

The OR operator retrieves records that contain any or all of the search terms. For example, the search heart attack or myocardial infarction retrieves results that contain the terms heart attack, myocardial infarction or both terms; results are all inclusive. You can use the OR operator in both unqualified searches and searches applied to a specific field.
AND x and y

generic and specific

"The patent family listed here contains generic and specific product claims to ambrisentan and relates to the VOLIBRIS and LETAIRIS formulations of ambrisentan."

 

The AND operator retrieves only those records that include all of the search terms. For example, the search blood pressure and stroke retrieves results that contain the term blood pressure and the term stroke together in the same record; results are exclusive of records that do not contain both of these terms. You can use the AND operator in both unqualified searches and searches applied to a specific field.
NOT x not y

generic not specific

"The medicament is either a protein or polypeptide but no specific drugs are claimed"

 

The NOT operator retrieves records that contain the first search term and excludes the second search term. For example, the search health reform not health maintenance organizations retrieves only those records that contain the term health reform but excludes the term health maintenance organizations. In this way, you can use the NOT operator to restrict results to a specific topic.
You can use the NOT operator in both unqualified searches and searches applied to a specific field.
Adjacency (ADJ) x y

generic adj name

"The marketed form of abacavir is the hemisulfate salt and has the generic name, abacavir sulfate."

 

The Adjacent operator (ADJ) retrieves records with search terms next to each other.You do not need to separate search terms manually by inserting ADJ between them, because when you separate terms with a space on the command line, Ovid automatically searches for the terms adjacent to one another. For example, the search blood pressure is identical to the search blood adj pressure.
Defined Adjacency (ADJn) x ADJn y

generic adj3 claims

"The earliest 7 relate to WO9427979,of ImmunoPharmaceutics, and are associated with generic claims to sitaxentan."

 

The defined adjacency operator (ADJn) retrieves records that contain search terms within a specified number (n) of words from each other in any order. To use the adjacency operator, separate your search terms with ADJ and a number from 1 to 99. For example, the search physician adj5 relationship retrieves records that contain the words physician and relationship within five words of each other in either direction. This particular search retrieves records containing such phrases as physician patient relationship, patient physician relationship, or relationship of the physician to the patient.
Unlimited Truncation ($) x$

pro$

"The patent family listed here claims a dosage form comprising a proton pump inhibitor, such as dexlansoprazole, and relates to the DEXILANT formulation of dexlansoprazole."
"thrombolytic, recombinant protein, biotechnology, protein, plasminogen activator"

 

Unlimited truncation retrieves all possible suffix variations of the root word indicated. To apply unlimited truncation to a term, type the root word or phrase followed by either of the truncation characters: $ (dollar sign) or * (asterisk). For example, in the truncated search disease*, Ovid retrieves the word disease as well as the words diseases, diseased, and more.
Limited Truncation ($) x$n

gen$1

"biotechnology, gene therapy"

 

Limited truncation specifies a maximum number of characters that may follow the root word or phrase. For example, the truncated search dog$1 retrieves results with the words dog and dogs; but it does not retrieve results with the word dogma.
Mandated Wildcard (#) xx#y

m#n

"The patent family listed here claims the use of letrozole in the treatment of detrusor urethral sphincter dyssynergia in men."

 

Searching with a mandated wildcard retrieves all possible variations of a word in which the wildcard is present in the specified place. You can use it at the end of a term to limit results to only those that contain the word plus the mandated character. For example, the search dog# retrieves results that contain the word dogs, but not those that contain the word dog, effectively limiting results to only those that contain the plural form of the word. The mandated wild card character (#) is also useful for retrieving specialized plural forms of a word. For example, the search wom#n retrieves results that contain both woman and women. You can use multiple wild cards in a single query word.
Optional Wildcard (?) xx?y

labo?r

"A2B3 Prostaglandin Antiulcerants, G2A Labour Inducers, R6A Systemic Antihistamines"

 

The optional wild card character (?) can be used within or at the end of a search term to substitute for one or no characters. This wild card is useful for retrieving documents with British and American word variants since it specifies that you want retrieval whether or not the extra character is present. For example, the optional wild card search colo?r retrieves results that contain the words color or colour. You can use multiple wild cards in a single query word.
Literal String ("") "x / y"

"extended/adjusted"

"The term of US 6730679 has been extended/adjusted by 236 days.

"sp"

20050629.sp.

"Expiry Date 20050629"

 

Quotation marks can be used to retrieve records that contain literal strings, when the string includes special characters, such as a forward slash (/).

Quotation marks can also be used to retrieve records that contain numbers that may otherwise be confused for earlier searches. In the example, a search for 3.vo would limit the string from your third search in your search history to the volume field. By including the number in quotation marks, the search will retrieve documents with a 3 in the volume number.

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Stopwords

The Ovid search engine applies so called "run-time stopword processing". This means the search engine on the fly ignores the stopwords: and, as, by, for, from, in, is, of, on, that, the, this, to, was, were & with.

Therefore a search: at risk for diabetes.ti will also find: at risk of diabetes. The distance of one word in between is kept, but the stopword "for" is ignored.

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Limits
The following limits are available for this database. See Database Limits in the Ovid Online Help for details on applying limits.

Limit

Syntax

Image

Sentence Syntax:

limit 1 to image

 

A limit to image restricts retrieval to documents containing an image of the drug compound. This limit will not greatly restrict the number of records and should not be used to narrow a search but only to enhance it.

Latest Update

Sentence Syntax:

limit 1 to latest update

 

A limit to latest update restricts retrieval to documents which were most recently added to the database.

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Tools
The following Search Tools are available for this database. For specific information on using these tools, refer to the Ovid Online Help linked below.
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Changing to this Database
To change a search session to a segment of this database from another database or another segment, use the following syntax in the Ovid Syntax tab:
  Command Syntax: ..c/pti
  Sentence Syntax: use pti
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Sample Documents
Sample 1
Accession Number
   0411239
Patent Number
   US8461187
Patent Type
   Drug delivery system
Patent Assignee
   Takeda (Belgium)
   Parent: Takeda (Japan)
Patent Publication Date
   20130611
Patent Family
   Dosage forms comprising dexlansoprazole - 2004
Patent Filing Date
   20050601
Patent Country
   USA
Drug Name
   dexlansoprazole, modified-release, drug delivery system
Synonyms
   drug delivery system, modified-release dexlansoprazole, Takeda, dexlansoprazole, dexlansoprazole, TAK
   390MR, KAPIDEX, DEXILANT
Highest Phase
   Marketed
Chemical Name
   2-[(R)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS Registry Numbers
   138530-94-6 (dexlansoprazole)
General Comments
   The patent family listed here claims a dosage form comprising a proton pump inhibitor, such as 
   dexlansoprazole, and relates to the DEXILANT formulation of dexlansoprazole.
Country Comments
   US patent US8461187 claims a dosage form comprising a proton pump inhibitor (PPI), where the PPI is 
   released from the dosage form as a first and a second dose. The first and second doses are released 
   from the dosage form as discreet pulses of the PPI separated by a period of time, where the second dose 
   contains at least 10% more of the PPI than the first dose, and where each of the first and second doses 
   comprise a sufficient amount of the PPI to raise plasma levels of thePPI to a concentration of at least 100 
   ng/ml.
   The term of US patent US8461187 has been extended/adjusted by 230 days under 35 U.S.C.154(b). As a 
   result the estimated expiry date of US patent US8461187 has been reset to 17 January 2026 from 1 June 
   2025.
   A pediatric extension of 6 months has been granted in the USA for US patent US8461187. The new expiry 
   date is 17 July 2026 from 17 January2026. The extension relates to the DEXILANT formulations of 
   dexlansoprazole.
   US patent US8461187 is quoted by the FDA Orange Book as relating to the DEXILANT delayed-release oral 
   capsule formulations of dexlansoprazole. The applicant is Takeda.
   US marketing exclusivity for the DEXILANT formulations of dexlansoprazole as a new product expired on 
   30 July 2012 (30 January 2012 plus 6-month pediatric extension).
Indication
   GERD
EphMRA Code
   A2B2 Acid Pump Inhibitors, V7A All Other Non-therapeutic Products
Latest Change
   20130726
Priority Details
   USA_US20040580265P_20040616
Expiry Information
   20260717, Granted (2013); Pediatric Extension Granted for DEXILANT
Patent Application Information
   20090827
   US2009215830
Mechanism of Action
   antifungal, imidazole, proton pump inhibitor
Update Code
   201307
Sample 2
Accession Number
   0411196
Patent Number
   AR255059
Patent Type
   Process to composition
Patent Assignee
   Astra (Sweden)
   Parent: AstraZeneca (UK)
Patent Publication Date
   20010518
Patent Family
   Processes for the preparation of a powder medicament comprising formoterol in combination with 
   budesonide - 1993
Patent Filing Date
   19940930
Patent Country
   Argentina
Drug Name
   budesonide + formoterol
Synonyms
   formoterol + budesonide, SYMBICORT
Highest Phase
   Marketed
Chemical Name
   (11beta,16alpha)-16,17-[butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
CAS Registry Numbers
   51333-22-3 (budesonide), 73573-87-2 (formoterol), 150693-37-1 (budesonide mixed with formoterol), 
   150693-38-2 (budesonide mixed with formoterol fumarate)
General Comments
   The patent family listed here claims a method for treating a finely divided powdered medicament, such as 
   formoterol in combination with budesonide.
Also claimed are agglomerates for use in the TURBUHALER breath-actuated dry powder inhaler.
This family relates to the SYMBICORT TURBUHALER formulation of formoterol in combination with budesonide.
Country Comments Argentinian patent AR255059 is based on WO9509615 and claims a methodof treatment of a finely divided powdered medicament having a primaryparticle size smaller than 10 mcm and poor flowing properties, to form, in a controlled manner, agglomerates or pellets that are free flowing and that are capable of breaking down to provide the finely divided medicament, the method comprising the steps of: - agglomerating the powdered medicament having particle sizes of lessthan 10 mcm by feeding the material to a screw feeder and letting thematerial pass through the screw feeder to obtain agglomerates; - spheronizing the resulting agglomerates in order to provide agglomerates that are more spherical, more dense and more compact than those obtained from the agglomeration process in the screw feeder; and - sizing the agglomerates to obtain a uniform size of the final product. Formoterol in combination with budesonide is claimed generically as the medicament. Indication asthma, COPD EphMRA Code R3F Combinations Of B2-stimulants With Corticoids Latest Change 20130725 Priority Details Sweden_SE19930003214_19931001 Sweden_SE19930004271_19931222 Expiry Information 20140930, Granted (2001) Mechanism of Action beta2 adrenergic agonist, fixed combination, corticosteroid, beta adrenergic agonist Update Code 201307
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Producer Information
Producer
QuintilesIMS
Formerly known as IMS Health
URL: http://www.imshealth.com/
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